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Article

Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.

Oncotarget - 19 Apr 2016

Lin Sheng-Yi, Lee Yue-Xun, Yu Sung-Liang, Chang Gee-Chen, Chen Jeremy J W

Abstract excerpt

Phosphatase of regenerating liver-3 (PRL-3) has been reported to be associated with colon and gastric cancer metastasis. However, the role and function of PRL-3 in human non-small cell lung cancer cells is unknown. Our studies showed that the expression of PRL-3mRNA and protein are higher in less invasive human lung adenocarcinoma cells than in highly invasive cell lines. Ectopic expression of PRL-3 reduced cell...

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Identifiers

PMID: 26967563
DOI: 10.18632/oncotarget.7985
PMCID: PMC5008324

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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