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Article

PRL phosphatases as potential molecular targets in cancer

1 Nov 2005

Abstract excerpt

The phosphatase of regenerating liver (PRL) family of phosphatases, consisting of PRL-1, PRL-2, and PRL-3, represents an intriguing group of proteins being validated as biomarkers and therapeutic targets in cancer. Individual PRLs are overexpressed in a variety of cancer cell lines and tissues when compared with their normal counterparts. More importantly, several recent studies have shown that PRL-3 is expressed...

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PMID: 16275986
DOI: 10.1158/1535-7163.mct-05-0248

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PRL phosphatases as potential molecular targets in cancerPMID 16275986Read ↗

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