Article
Increased expression of the PRL-3 gene in human oral squamous cell carcinoma and dysplasia tissues.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Hassan Nur Mohammad Monsur, Hamada Jun-ichi, Kameyama Takeshi, Tada Mitsuhiro, Nakagawa Koji, Yoshida Shoko, Kashiwazaki Haruhiko, Yamazaki Yutaka, Suzuki Yukiko, Sasaki Akira, Nagatsuka Hitoshi, Inoue Nobuo, Moriuchi Tetsuya
Abstract excerpt
Phosphatase of regenerating liver (PRL) belongs to a class of the protein tyrosine phosphatase family, which is known so far to consist of 3 members, PRL-1, PRL-2, and PRL-3. The aim of this study was to uncover the role of PRL genes in development of oral malignancy. We analyzed expression levels of the 3 PRL genes in 50 human oral squamous cell carcinomas (OSCCs), 11 dysplasia and 12 normal mucosa tissues by a...
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