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Article

Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels.

PloS one - 1 Jan 2019

Geiger Florian, Rüdiger Daniel, Zahler Stefan, Engelke Hanna

Abstract excerpt

Cancer cell migration is influenced by cellular phenotype and behavior as well as by the mechanical and chemical properties of the environment. Furthermore, many cancer cells show plasticity of their phenotype and adapt it to the properties of the environment. Here, we study the influence of fiber stiffness, confinement, and adhesion properties on cancer cell migration in porous collagen gels. Collagen gels with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31721794
DOI: 10.1371/journal.pone.0225215
PMCID: PMC6853323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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