Actomyosin tension as a determinant of metastatic cancer mechanical tropism.

Abstract excerpt

Despite major advances in the characterization of molecular regulators of cancer growth and metastasis, patient survival rates have largely stagnated. Recent studies have shown that mechanical cues from the extracellular matrix can drive the transition to a malignant phenotype. Moreover, it is also known that the metastatic process, which results in over 90% of cancer-related deaths, is governed by intracellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Actomyosin
• Share to Cell Adhesion
• Share to Cell Movement