Article
Actomyosin tension as a determinant of metastatic cancer mechanical tropism.
Physical biology - 23 Feb 2015
McGrail Daniel J, Kieu Quang Minh N, Iandoli Jason A, Dawson Michelle R
Abstract excerpt
Despite major advances in the characterization of molecular regulators of cancer growth and metastasis, patient survival rates have largely stagnated. Recent studies have shown that mechanical cues from the extracellular matrix can drive the transition to a malignant phenotype. Moreover, it is al...
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