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Article

ERBB2 overexpression triggers transient high mechanoactivity of breast tumor cells

7 Mar 2012

Abstract excerpt

Biomechanical properties of tumor cells play an important role for the metastatic capacity of cancer. Cellular changes of viscoelastic features are prerequisite for cancer progression since they are essential for proliferation and metastasis. However, only little is known about the way how expression of oncogenes influences these biomechanical properties. To address this aspect we used a breast cancer cell line...

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PMID: 22407943
DOI: 10.1002/cm.21023

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