Article

Mechanotranscriptomic Profiling of Breast Cancer Cells Intravasated from Engineered Microtumors

2026-03-03

Abstract excerpt

Intravasation is the process by which cancer cells breach the physical boundaries of a primary tumor and enter blood or lymphatic vessels. In this work, MCF-7 breast cancer cells were cultured within polymer-based microcapsules (here referred to as artificial microtumors) to investigate the transcriptomic and morpho-mechanical changes occurring in cancer cells during their release from these matrices, mimicking in...

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Literature Corpus work: a9d735d9-cc0d-5f3c-b161-8853fb7b6d24
DOI: 10.64898/2026.02.28.708725

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