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Article

Cytochrome P450 2C8*2 allele in Botswana: Human genetic diversity and public health implications.

Acta tropica - 1 May 2016

Motshoge Thato, Tawe Leabaneng, Muthoga Charles Waithaka, Allotey Joel, Romano Rita, Quaye Isaac, Paganotti Giacomo Maria

Abstract excerpt

Human cytochrome P450 2C8 is a highly polymorphic gene and shows variation according to ethnicity. The CYP2C8*2 is a slow drug metabolism allele and shows 10-24% frequency in Black populations. The objective of this study was to assess the prevalence of CYP2C8*2 allele in Botswana among the San (or Bushmen) and the Bantu ethnic groups. For that purpose we recruited 544 children of the two ethnicities in three...

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Identifiers

PMID: 26836270
DOI: 10.1016/j.actatropica.2016.01.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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