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Article

CYP2C8 polymorphism frequencies among malaria patients in Zanzibar.

European journal of clinical pharmacology - 1 Mar 2005

Cavaco I, Strömberg-Nörklit J, Kaneko A, Msellem M I, Dahoma M, Ribeiro V L, Bjorkman A, Gil J P

Abstract excerpt

OBJECTIVE: The determination of the prevalence of the CYP2C8 main alleles in a typical set of malaria patients in Zanzibar, as these patients represent a typical population exposed to amodiaquine, an antimalarial mainly metabolized by CYP2C8. Also, to determine for the first time the frequencies of CYP2C8 alleles in native African populations. METHODS: Polymerase chain reaction-restriction fragment polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15785959
DOI: 10.1007/s00228-004-0871-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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