Article
[CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups].
Terapevticheskii arkhiv - 15 Nov 2021
Abdullaev S P, Denisenko N P, Mirzaev K B, Shuev G N, Sozaeva Z A, Kachanova A A, Mammaev S N, Kasaeva E A, Gafurov D M, Grishina E A, Sychev D A
Abstract excerpt
AIM: Find the prevalence of CYP2C8*3 (rs10509681; rs11572080), PTGS-1 (rs10306135; rs12353214) and PTGS-2 (rs20417) alleles and genotypes in four ethnic groups among Laks, Avars, Dargins and Kumyks. MATERIALS AND METHODS: The study involved 400 volunteers from four ethnic groups living in Republic of Dagestan: 100 participants from each group. Carriage of polymorphic markers was determined by reverse...