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Article

Genetic variability of glutathione S-transferase enzymes in human populations: functional inter-ethnic differences in detoxification systems.

Gene - 1 Jan 2013

Polimanti Renato, Carboni Cinzia, Baesso Ilenia, Piacentini Sara, Iorio Andrea, De Stefano Gian Franco, Fuciarelli Maria

Abstract excerpt

Glutathione S-Transferase enzymes (GSTs) constitute the principal Phase II superfamily which plays a key role in cellular detoxification and in other biological processes. Studies of GSTs have revealed that genetic polymorphisms are present in these enzymes and that some of these are Loss-of-Function (LoF) variants, which affect enzymatic functions and are related to different aspects of human health. The aim of...

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Source

Identifiers

PMID: 23043933
DOI: 10.1016/j.gene.2012.09.113

Genes

GSTA1
GSTM1
GSTO1
GSTO2
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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