Article
CYP2D6 variability in populations from Venezuela.
Drug metabolism and personalized therapy - 1 Dec 2016
Moreno Nancy, Flores-Angulo Carlos, Villegas Cecilia, Mora Yuselin
Abstract excerpt
CYP2D6 is an important cytochrome P450 enzyme that plays an important role in the metabolism of about 25% of currently prescribed drugs. The presence of polymorphisms in the CYP2D6 gene may modulate enzyme level and activity, thereby affecting individual responses to pharmacological treatments. The most prevalent diseases in the admixed population from Venezuela are cardiovascular and cancer, whereas viral,...
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