Article
Frequency of -163 C>A and 63 C>G single nucleotide polymorphism of cytochrome P450 1A2 in two African populations.
Clinical chemistry and laboratory medicine - 1 Jan 2004
Dandara Collet, Basvi Patience T, Bapiro Tashinga E, Sayi Jane, Hasler Julia A
Abstract excerpt
Cytochrome P450 1A2 (CYP1A2) is an important member of the cytochrome P450 superfamily of enzymes because of its involvement in the metabolism of some carcinogens and therapeutically important drugs. As a result, factors affecting the activity of the enzyme are the focus of considerable research effort as they may have important pharmacological or toxicological implications. CYP1A2 has been shown to exhibit a...
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