Prevalence of G6PD deficiency and associated haematological parameters in children from Botswana.

doi:10.1016/j.meegid.2018.05.014

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Article

Prevalence of G6PD deficiency and associated haematological parameters in children from Botswana.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2018

Motshoge Thato, Ababio Grace, Aleksenko Larysa, Souda Sajini, Muthoga Charles Waithaka, Mutukwa Naledi, Tawe Leabaneng, Ramatlho Pleasure, Gabaitiri Lesego, Chihanga Simon, Mosweunyane Tjantilili, Hamda Shimeles, Moakofhi Kentse, Ntebela Davies, Peloewetse Elias, Mazhani Loeto, Pernica Jeffrey M, Read John, Quaye Isaac Kweku, Paganotti Giacomo Maria

Abstract excerpt

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is commonly seen in malaria endemic areas as it is known to confer a selective advantage against malaria. Recently, we reported a high proportion of asymptomatic reservoir of Plasmodium vivax in Botswana, that calls for intervention with primaquine to achieve radical cure of vivax malaria. Considering that individuals with this enzyme deficiency are at risk of...

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PMID: 29778768
DOI: 10.1016/j.meegid.2018.05.014

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