Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.

doi:10.1177/0271678X15626719

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Article

Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Apr 2016

Felsky Daniel, De Jager Philip L, Schneider Julie A, Arfanakis Konstantinos, Fleischman Debra A, Arvanitakis Zoe, Honer William G, Pouget Jennie G, Mizrahi Romina, Pollock Bruce G, Kennedy James L, Bennett David A, Voineskos Aristotle N

Abstract excerpt

The translocator protein, a microglial-expressed marker of neuroinflammation, has been implicated in Alzheimer's disease, which is characterized by alterations in vascular and inflammatory states. ATSPOvariant, rs6971, determines binding affinity of exogenous radioligandsin vivo; however, the effect of these altered binding characteristics on inflammatory and cerebrovascular biomarkers has not been assessed. In...

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Identifiers

PMID: 26762507
DOI: 10.1177/0271678X15626719
PMCID: PMC4821029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.PMID 26762507Read ↗

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