Article
Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.
Synapse (New York, N.Y.) - 1 Nov 2014
Suridjan Ivonne, Rusjan Pablo M, Kenk Miran, Verhoeff Nicolaas Paul L G, Voineskos Aristotle N, Rotenberg David, Wilson Alan A, Meyer Jeffrey H, Houle Sylvain, Mizrahi Romina
Abstract excerpt
The ability to quantify translocator protein 18 kDa (TSPO) in white matter (WM) is important to understand the role of neuroinflammation in neurological disorders with WM involvement. This article aims to extend the utility of TSPO imaging in WM using a second-generation radioligand, [18F]-FEPPA, and high-resolution research tomograph (HRRT) positron emission tomography (PET) camera system. Four WM regions of...
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