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Article

The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: a [¹¹C]PBR28 PET study.

Brain, behavior, and immunity - 1 Oct 2013

Hannestad Jonas, DellaGioia Nicole, Gallezot Jean-Dominique, Lim Keunpoong, Nabulsi Nabeel, Esterlis Irina, Pittman Brian, Lee Jae-Yun, O'Connor Kevin C, Pelletier Daniel, Carson Richard E

Abstract excerpt

Depression is associated with systemic inflammation. In animals, systemic inflammation can induce neuroinflammation and activation of microglia; however, postmortem studies have not convincingly shown that there is neuroinflammation in depression. The purpose of this study was to use positron emission tomography (PET) with [¹¹C]PBR28, which binds to the neuroinflammation marker translocator protein 18 kDa (TSPO),...

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Identifiers

PMID: 23850810
DOI: 10.1016/j.bbi.2013.06.010
PMCID: PMC3899398

Genes

TSPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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