Article
Genetic polymorphisms analysis of drug-metabolizing enzyme CYP2C9 in the Uyghur population.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Aug 2016
Jin Tianbo, Xun Xiaojie, Du Shuli, Geng Tingting, Wang Hong, Feng Tian, Chen Chen, Yuan Dongya, Kang Longli
Abstract excerpt
Genetic variations in cytochrome P450 2C9 are known to contribute to interindividual and interethnic variability in response to clinical drugs, but little is known about the genetic variation of CYP2C9 in the Uyghur population. We directly sequenced the whole CYP2C9 gene in 96 unrelated, healthy Uyghur from Xinjiang Uygur Autonomous Region of China and screened for genetic variants in the promoter, exons, introns...
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