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Article

Molecular functionality of CYP2C9 polymorphisms and their influence on drug therapy.

Drug metabolism and drug interactions - 1 Jan 2014

Jarrar Yazun Bashir, Lee Su-Jun

Abstract excerpt

CYP2C9 metabolizes approximately 20% of clinically used drugs, including the narrow therapeutic window drugs warfarin and phenytoin. More than 16,000 variants have been reported in the National Center for Biotechnology Information CYP2C9 database, as well as 58 alleles in the official P450 Nomenclature Committee website. Two single nucleotide polymorphisms represented by the CYP2C9*2 and CYP2C9*3 alleles have...

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Source

Identifiers

PMID: 24825094
DOI: 10.1515/dmdi-2014-0001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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