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Genetic and phenotypic frequency distribution of CYP2C9, CYP2C19 and CYP2D6 in over 3200 Han Chinese.

Clinical and experimental pharmacology & physiology - 1 Oct 2020

He Li, Chen Shaojun, Li Jingao, Xie Xiaoxue, Huang Lihua, Kuang Yun, Xu Kangwei, Huang Wanxia, Zhao Yanling, Yang Guoping, Guo Chengxian

Abstract excerpt

PURPOSE: This retrospective study analyzed the polymorphisms and phenotypic frequencies of CYP2C9, CYP2C19 and CYP2D6 in a Han Chinese population. METHODS: Tests for polymorphisms of CYP2C9, CYP2C19 and CYP2D6 were performed in over 3000 (3099-3931) samples using an Illumina HiSeq X Ten sequencer. Following the guidance of the PharmGKB and PharmVar databases, the polymorphisms of CYP2C9, CYP2C19 and CYP2D6 were...

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PMID: 32469422
DOI: 10.1111/1440-1681.13357

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