Article
Genetic polymorphism analysis of the drug-metabolizing enzyme CYP2C9 in a Chinese Tibetan population.
Gene - 10 Aug 2015
Jin Tianbo, Geng Tingting, He Na, Shi Xugang, Wang Li, Yuan Dongya, Kang Longli
Abstract excerpt
OBJECTIVES: The enzymatic activity of CYP2C9 results in broad inter-individual variability in response to certain pharmacotherapies. The present study aimed to screen Tibetan volunteers for CYP2C9 genetic polymorphisms. Previous research has focused on Han Chinese patients, while little is known about the genetic variation of CYP2C9 in Tibetan populations. METHODS: We used DNA sequencing to investigate the...
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