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Genetic variation of cytochrome P450 in Uyghur Chinese population.

Drug metabolism and pharmacokinetics - 1 Feb 2018

Qi Guangzhao, Li Duolu, Zhang Xiaojian

Abstract excerpt

Interindividual and interethnic variability of drug responses could be attributed to the differences of genetic polymorphisms in the drug metabolizing enzymes and transporters genes among the populations. Here we reviewed the studies of genetic variations in Uyghur Chinese of fifteen CYP450 genes including CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP2J2, CYP2W1, CYP3A4, CYP3A5,...

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PMID: 29233455
DOI: 10.1016/j.dmpk.2017.02.002

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