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Article

Genetic polymorphisms analysis of CYP2D6 in the Uygur population.

BMC genomics - 26 May 2016

He Xue, He Na, Ren Lisong, Ouyang Yongri, Zhang Ning, Ma Yini, Yuan Dongya, Kang Longli, Jin Tianbo

Abstract excerpt

BACKGROUND: This study aimed to investigate genetic polymorphisms of CYP2D6 among healthy Uygur individuals. Genetic polymorphisms of CYP2D6 could greatly affect CYP2D6 activity and lead to differences among individuals in drug efficacy or side effects. To investigate genetic polymorphisms of CYP2D6 in the Uygur population, we directly sequenced the whole gene in 96 unrelated, healthy Uygur volunteers from the...

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Identifiers

PMID: 27228982
DOI: 10.1186/s12864-016-2719-x
PMCID: PMC4882831

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