Article
Genetic polymorphisms and phenotypic analysis of drug-metabolizing enzyme CYP2C19 in a Li Chinese population.
International journal of clinical and experimental pathology - 1 Jan 2015
Ding Yipeng, Xu Dongchuan, Zhang Xiyang, Yang Hua, Geng Tingting, He Ping, Yao Jinjian, Yi Shengyang, Xu Heping, Wu Duoyi, Wang Xiang, Jin Tianbo
Abstract excerpt
CYP2C19 is a highly polymorphic gene and CYP2C19 enzyme results in broad inter-individual variability in response to certain clinical drugs, while little is known about the genetic variation of CYP2C19 in Li Chinese population. The aim of this study was to identify different CYP2C19 mutant alleles and determine their frequencies, along with genotype frequencies, in the Li Chinese population. We used DNA...
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