Article
A systematic genetic polymorphism analysis of the CYP2C9 gene in four different geographical Han populations in mainland China.
Genomics - 1 May 2011
Xiong Yuyu, Wang Ming, Fang Ke, Xing Qinghe, Feng Guoyin, Shen Lu, He Lin, Qin Shengying
Abstract excerpt
While many studies have been focused on CYP2C9*2 and *3 there was a lack of large full gene sequencing on CYP2C9, and this study was designed to fill this gap. We used direct sequencing to systematically screen genetic polymorphisms of the CYP2C9 gene including the 5' -flanking region (2kb), all exons and their adjoining intron regions and the 3' UTR in 400 unrelated healthy Chinese Han volunteers. A total of 27...
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