Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significant association of the KIR2DL3/HLA-C1 genotype with susceptibility to Crohn's disease.

Human immunology - 1 Jan 2016

Díaz-Peña Roberto, Vidal-Castiñeira Jose Ramón, Moro-García Marco Antonio, Alonso-Arias Rebeca, Castro-Santos Patricia

Abstract excerpt

We aimed to analyze the possible association of KIR/HLA-C genotypes with the susceptibility to Crohn's disease (CD) in a Spanish population. A total of 125 patients with CD and 339 healthy controls were selected for this study. KIR and HLA-C typing were developed by sequence-specific oligonucleotide probing. We found that the centromeric A/A genotype and HLA-C1 combination was significantly increased in CD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crohn Disease
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

Share to Killer Cells, Natural

Share to Linkage Disequilibrium

Share to Receptors, KIR2DL2

Share to Receptors, KIR2DL3

Source

Identifiers

PMID: 26542067
DOI: 10.1016/j.humimm.2015.10.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significant association of the KIR2DL3/HLA-C1 genotype with susceptibility to Crohn's disease.PMID 26542067Read ↗

Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand.Semantic proximity Read ↗

Contribution of KIR genes, HLA class I ligands, and KIR/HLA class I ligand combinations on the genetic predisposition to celiac disease and coexisting celiac disease and type 1 diabetes mellitus.Semantic proximity Read ↗

The missense variation Q705K in CIAS1/NALP3/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease.Semantic proximity Read ↗

KIR/HLA combination associated with the risk of complications in celiac disease.Semantic proximity Read ↗

Killer immunoglobulin-like receptor repertoire analysis in a Caucasian Spanish cohort with inflammatory bowel disease.Semantic proximity Read ↗

The role of killer-cell immunoglobulin-like receptor (KIR) genes in susceptibility to inflammatory bowel disease: systematic review and meta-analysis.Semantic proximity Read ↗

HLA-C*01 is a Risk Factor for Crohn's Disease.Semantic proximity Read ↗

Association between KIR-HLA combination and ulcerative colitis and Crohn's disease in a Japanese population.Semantic proximity Read ↗

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.Semantic proximity Read ↗

HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility.Semantic proximity Read ↗

Susceptibility to severe ulcerative colitis is associated with polymorphism in the central MHC gene IKBL.Semantic proximity Read ↗

Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.