Article
Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.
Genes and immunity - 1 Mar 2007
Santin I, Castellanos-Rubio A, Perez de Nanclares G, Vitoria J C, Castaño L, Bilbao J R
Abstract excerpt
Genome-wide scans have detected linkage to celiac disease (CD) in several genomic locations, including 19q13.4. Killer immunoglobulin-like receptor (KIR) genes map to the region and encode receptors of natural killer (NK) cells and certain T cells that modulate cytolitic activity through interactions with HLA class I ligands, participating in the innate immune response. We performed KIR genotyping in a group of...
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