Article
Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases.
Journal of immunology research - 1 Jan 2020
Beigmohammadi Fereshteh, Mahmoudi Mahdi, Karami Jafar, Ahmadzadeh Nooshin, Ebrahimi-Daryani Nasser, Rezaei Nima
Abstract excerpt
Genetic studies have illustrated that killer cell immunoglobulin-like receptor (KIR) genes could participate in various autoimmune disorders. We aimed to clarify the role of KIR genes, HLA ligands, HLA-KIR interactions, and their genotypes in inflammatory bowel disease (IBD) susceptibility. The study population was composed of 183 IBD subjects, comprising 100 ulcerative colitis (UC) patients, 83 Crohn's disease...
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