Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases.

doi:10.1155/2020/4873648

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Article

Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases.

Journal of immunology research - 1 Jan 2020

Beigmohammadi Fereshteh, Mahmoudi Mahdi, Karami Jafar, Ahmadzadeh Nooshin, Ebrahimi-Daryani Nasser, Rezaei Nima

Abstract excerpt

Genetic studies have illustrated that killer cell immunoglobulin-like receptor (KIR) genes could participate in various autoimmune disorders. We aimed to clarify the role of KIR genes, HLA ligands, HLA-KIR interactions, and their genotypes in inflammatory bowel disease (IBD) susceptibility. The study population was composed of 183 IBD subjects, comprising 100 ulcerative colitis (UC) patients, 83 Crohn's disease...

Topics

Adult
Alleles
Disease Susceptibility
Female
Genetic Predisposition to Disease
Genotype
HLA Antigens
Humans
Inflammatory Bowel Diseases
Killer Cells, Natural
Ligands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Odds Ratio

Protein Binding

Receptors, KIR

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 33015197
DOI: 10.1155/2020/4873648
PMCID: PMC7520679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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