Article
Contribution of KIR genes, HLA class I ligands, and KIR/HLA class I ligand combinations on the genetic predisposition to celiac disease and coexisting celiac disease and type 1 diabetes mellitus.
Revista espanola de enfermedades digestivas - 1 Sept 2015
Akar H Haluk, Patiroglu Turkan, Sevinc Eylem, Aslan Duran, Okdemir Deniz, Kurtoglu Selim
Abstract excerpt
BACKGOUND AND AIM: There are some common genetic features between celiac disease (CD) and diabetes mellitus type 1 (DM). However, the genetic risk factors have not been fully clarified for CD and the co-occurrence of CD and DM. KIR (killer immunoglobulin-like receptor) genes regulate the cytolitic activity of NK-cells and T lymphocytes. The aim of this study is to evaluate the contribution of KIR genes, KIR...
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