Article
KIR/HLA combination associated with the risk of complications in celiac disease.
The International journal of biological markers - 1 Jan 2000
Caggiari Laura, Toffoli Giuseppe, De Re Valli, Orzes Nicoletta, Spina Michele, De Zorzi Mariangela, Maiero Stefania, Cannizzaro Renato, Canzonieri Vincenzo
Abstract excerpt
The pathogenesis of celiac disease (CD) is associated with polymorphisms in human leukocyte antigen (HLA) genes; however, compelling evidence suggests that additional non-HLA genes are associated with CD and related complications. The present study investigated whether killer cell immunoglobulin-like receptor (KIR)/HLA gene combinations are associated with CD and its clinical complications in the population of...
Topics
- Adolescent
- Adult
- Aged
- Celiac Disease
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- HLA Antigens
- Humans
- Male
