Article
HLA-C*01 is a Risk Factor for Crohn's Disease.
Inflammatory bowel diseases - 1 Apr 2016
Jung Eun Suk, Cheon Jae Hee, Lee Ji Hyun, Park Soo Jung, Jang Hui Won, Chung Sook Hee, Park Myoung Hee, Kim Tai-Gyu, Oh Heung-Bum, Yang Suk-Kyun, Park Sang Hyoung, Han Jae Yong, Hong Sung Pil, Kim Tae Il, Kim Won Ho, Lee Min Goo
Abstract excerpt
BACKGROUND: A dysregulated mucosal immune response to the intestinal environment in a genetically susceptible host is hypothesized to be critical to the pathogenesis of Crohn's disease (CD). Therefore, we examined CD-susceptibility genes involved in the immune response through a genome-wide association study and consecutive genotyping of human leukocyte antigens (HLAs) and killer cell immunoglobulin-like...
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