Article
The role of killer-cell immunoglobulin-like receptor (KIR) genes in susceptibility to inflammatory bowel disease: systematic review and meta-analysis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Sept 2018
Fathollahi Anwar, Aslani Saeed, Mostafaei Shayan, Rezaei Nima, Mahmoudi Mahdi
Abstract excerpt
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic inflammatory disease, which involves the gut and comprises of Crohn's disease (CD) and ulcerative colitis (UC). Immune cells, including natural killer (NK) cells, play an important role in the pathogenesis of the disease. Killer immunoglobulin-like receptors (KIRs) are NK cell surface receptors, which ligate to the class I major histocompatibility complex...
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