Article
Killer immunoglobulin-like receptor repertoire analysis in a Caucasian Spanish cohort with inflammatory bowel disease.
Microbiology and immunology - 1 Nov 2016
López-Hernández Ruth, Campillo Jose A, Legaz Isabel, Valdés Mariano, Salama Hortensia, Boix Francisco, Hernández-Martínez A M, Eguia Jorge, González-Martínez G, Moya-Quiles Maria R, Minguela Alfredo, García-Alonso Ana, Carballo Fernando, Muro Manuel
Abstract excerpt
Immunological molecules are implicated in inflammatory disorders, including inflammatory bowel disease (IBD; Crohn disease [CD] and ulcerative colitis [UC]). Killer cell immunoglobulin-like receptors (KIRs) are also genetically variable proteins involved in immune function. They are expressed by NK cells and certain T lymphocytes, regulate specificity and function by interaction with HLA Class I molecules, may be...
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