HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility.

doi:10.1038/pr.2012.133

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Article

HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility.

Pediatric research - 1 Dec 2012

Krini Maro, Chouliaras Giorgos, Kanariou Maria, Varela Ioanna, Spanou Kleopatra, Panayiotou Joanna, Roma Eleftheria, Constantinidou Nikki

Abstract excerpt

BACKGROUND: Celiac disease (CD) has been associated with HLA class II heterodimers. This study aimed at determining the HLA genotypic and allelic distribution in Greek children with CD as compared with the general population. METHODS: A total of 118 children with CD and 120 healthy individuals serving as controls were included in the study. RESULTS: Higher frequencies for HLA-DQB1*02:01 (40.25 vs. 9.58%, P <...

Topics

Celiac Disease
Child
Genetic Predisposition to Disease
Genotype
Greece
Histocompatibility Antigens Class II
Humans

Source

Open in PubMed

Identifiers

PMID: 23041663
DOI: 10.1038/pr.2012.133

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