Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP2A6 Effects on Subjective Reactions to Initial Smoking Attempt.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 May 2016

Cannon Dale S, Mermelstein Robin J, Medina Tait R, Pugach Oksana, Hedeker Donald, Weiss Robert B

Abstract excerpt

INTRODUCTION: In very novice smokers, CYP2A6 genotypes that reduce nicotine metabolism to an intermediate rate may increase smoking risk, relative to both normal and slow rates. The present study examined the hypothesis that intermediate metabolism variants are associated with greater pleasurable effects of the initial smoking attempt than either normal or slow metabolism variants. METHODS: Participants were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aryl Hydrocarbon Hydroxylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2A6

Share to Nicotine

Share to Risk Factors

Share to Smoking

Share to Smoking Cessation

Share to Tobacco Use Disorder

Source

Open in PubMed Open full text

Identifiers

PMID: 26541911
DOI: 10.1093/ntr/ntv244
PMCID: PMC5896830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP2A6 Effects on Subjective Reactions to Initial Smoking Attempt.PMID 26541911Read ↗

CYP2A6 Longitudinal Effects in Young Smokers.Semantic proximity Read ↗

CYP2A6 metabolism in the development of smoking behaviors in young adults.Semantic proximity Read ↗

Nicotine Metabolism Predicted by CYP2A6 Genotypes in Relation to Smoking Cessation: A Systematic Review.Semantic proximity Read ↗

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.Semantic proximity Read ↗

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.Semantic proximity Read ↗

Variation in CYP2A6 and tobacco dependence throughout adolescence and in young adult smokers.Semantic proximity Read ↗

The role of CYP2A6 in the emergence of nicotine dependence in adolescents.Semantic proximity Read ↗

Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.Semantic proximity Read ↗

Impact of CYP2A6 Activity on Nicotine Reinforcement and Cue-Reactivity in Daily SmokersSemantic proximity Read ↗

Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activitySemantic proximity Read ↗

Determinants of the rate of nicotine metabolism and effects on smoking behavior.Semantic proximity Read ↗

Influence of CYP2A6 Genetic Variation, Nicotine Dependence Severity, and Treatment on Smoking Cessation Success.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.