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Article

The role of CYP2A6 in the emergence of nicotine dependence in adolescents.

Pediatrics - 1 Jan 2007

Audrain-McGovern Janet, Al Koudsi Nael, Rodriguez Daniel, Wileyto E Paul, Shields Peter G, Tyndale Rachel F

Abstract excerpt

OBJECTIVES: The objectives of our study were to evaluate whether genetic variation in nicotine metabolic inactivation accounted for the emergence of nicotine dependence from mid- to late adolescence and whether initial smoking experiences mediated this effect. METHODS: Participants were 222 adolescents of European ancestry who participated in a longitudinal cohort study of the biobehavioral determinants of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17130279
DOI: 10.1542/peds.2006-1583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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