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Article

Nicotine Metabolism Predicted by CYP2A6 Genotypes in Relation to Smoking Cessation: A Systematic Review.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 26 Mar 2022

Jones Stephanie K, Wolf Bethany J, Froeliger Brett, Wallace Kristin, Carpenter Matthew J, Alberg Anthony J

Abstract excerpt

INTRODUCTION: Identifying genetic factors associated with smoking cessation could inform precision cessation interventions. Of major interest is genetic variation in nicotine metabolism, largely predicted by CYP2A6 variations. AIMS AND METHODS: We conducted a systematic literature review to summarize the population-based evidence of the association between CYP2A6 and smoking cessation. In the 12 studies meeting...

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Identifiers

PMID: 34478556
DOI: 10.1093/ntr/ntab175
PMCID: PMC9122756

Genes

CYP2A6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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