Article
Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL.
Journal of immunology research - 1 Jan 2015
Zhang Yue-Miao, Cheng Fa-Juan, Zhou Xu-Jie, Qi Yuan-Yuan, Hou Ping, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
Objectives. Numerous loci were identified to perturb gene expression in trans. As elevated ATG5 expression was observed in systemic lupus erythematosus (SLE), the study was conducted to analyze the genome-wide genetic regulatory mechanisms associated with ATG5 expression in a Chinese population with lupus nephritis (LN). Methods. The online expression quantitative trait loci database was searched for...
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