Article
Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese.
Oncotarget - 21 Feb 2017
Zhang Yue-Miao, Zhou Xu-Jie, Cheng Fa-Juan, Qi Yuan-Yuan, Hou Ping, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
Autophagy is associated with various immune diseases, including systemic lupus erythematosus (SLE). Seven variants within autophagy-related genes previously reported to show top association signals by genome-wide association studies in immune diseases were selected for analysis. Initially, 510 SLE patients (631 controls) were enrolled in the study. An additional independent cohort of 511 SLE patients (687...
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