Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of expression quantitative trait loci (eQTLs) in human peripheral blood mononuclear cells (PBMCs) and shared with liver and brain.

Journal of cellular biochemistry - 1 Feb 2018

He Pei, Xia Wei, Wang Lan, Wu Jian, Guo Yu-Fan, Zeng Ke-Qin, Wang Ming-Jun, Bing Peng-Fei, Xie Fang-Fei, Lu Xin, Zhang Yong-Hong, Lei Shu-Feng, Deng Fei-Yan

Abstract excerpt

PBMCs are essential for immunity and involved in various diseases. To identify genetic variations contributing to PBMCs transcriptome-wide gene expression, we performed a genome-wide eQTL analysis by using genome-wide SNPs data and transcriptome-wide mRNA expression data. To assess whether there are common regulation patterns shared among different tissues/organs, public datasets were utilized to identify common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Gene Regulatory Networks

Share to Leukocytes, Mononuclear

Share to Mutation, Missense

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 28792098
DOI: 10.1002/jcb.26325

Genes

EGLN3
HSPB8
TIPRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of expression quantitative trait loci (eQTLs) in human peripheral blood mononuclear cells (PBMCs) and shared with liver and brain.PMID 28792098Read ↗

Integrative multi-omics analysis revealed SNP-lncRNA-mRNA (SLM) networks in human peripheral blood mononuclear cells.Semantic proximity Read ↗

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.Semantic proximity Read ↗

Systematic identification of trans eQTLs as putative drivers of known disease associations.Semantic proximity Read ↗

Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of DiseasesSemantic proximity Read ↗

Whole genome DNA and RNA sequencing of whole blood elucidates the genetic architecture of gene expression underlying a wide range of diseases.Semantic proximity Read ↗

Identification of context-dependent expression quantitative trait loci in whole blood.Semantic proximity Read ↗

Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of DiseasesSemantic proximity Read ↗

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data.Semantic proximity Read ↗

Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease.Semantic proximity Read ↗

Single-cell RNA sequencing reveals cell-type specific <i>cis</i> -eQTLs in peripheral blood mononuclear cellsSemantic proximity Read ↗

Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders.Semantic proximity Read ↗

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.