Article
Rare Variants of ATG5 Are Likely to Be Associated With Chinese Patients With Systemic Lupus Erythematosus.
Medicine - 1 Jun 2015
Zhang Yue-Miao, Cheng Fa-Juan, Zhou Xu-Jie, Qi Yuan-Yuan, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
Recently, common variants within or near ATG5, which is a key autophagy gene required for the formation of autophagosomes, have been identified as a candidate gene of systemic lupus erythematosus (SLE) by several genome-wide association studies. Moreover, elevated ATG5 expression was observed in SLE as well as other autoimmune diseases. However, no significant associations between variants within ATG5 and SLE...
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