Article
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.
PLoS genetics - 12 Feb 2010
Yang Wanling, Shen Nan, Ye Dong-Qing, Liu Qiji, Zhang Yan, Qian Xiao-Xia, Hirankarn Nattiya, Ying Dingge, Pan Hai-Feng, Mok Chi Chiu, Chan Tak Mao, Wong Raymond Woon Sing, Lee Ka Wing, Mok Mo Yin, Wong Sik Nin, Leung Alexander Moon Ho, Li Xiang-Pei, Avihingsanon Yingyos, Wong Chun-Ming, Lee Tsz Leung, Ho Marco Hok Kung, Lee Pamela Pui Wah, Chang Yuk Kwan, Li Philip H, Li Ruo-Jie, Zhang Lu, Wong Wilfred Hing Sang, Ng Irene Oi Lin, Lau Chak Sing, Sham Pak Chung, Lau Yu Lung
Abstract excerpt
Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altogether involving a total of 3,300 Asian SLE patients from Hong Kong, Mainland China, and Thailand, as well as 4,200 ethnically and geographically matched controls,...
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