Article
Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.
Frontiers in immunology - 1 Jan 2022
Song Kangkang, Zheng Xiaodong, Liu Xiaomin, Sheng Yujun, Liu Lu, Wen Leilei, Shang Shunlai, Deng Yiyao, Ouyang Qing, Sun Xuefeng, Li Qinggang, Chen Pu, Cai Guangyan, Chen Mengyun, Zhang Yuanjing, Liang Bo, Zhang Jianglin, Zhang Xuejun, Chen Xiangmei
Abstract excerpt
Background: Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythaematosus (SLE). Genetic factors play important roles in the pathogenesis of LN and could be used to predict who might develop LN. The purpose of this study was to screen for susceptible candidates of LN across the whole genome in the Han Chinese population. Methods: 592 LN patients and 453 SLE patients...
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