Article
Brief Report: identification of MTMR3 as a novel susceptibility gene for lupus nephritis in northern Han Chinese by shared-gene analysis with IgA nephropathy.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Oct 2014
Zhou Xu-Jie, Nath Swapan K, Qi Yuan-Yuan, Cheng Fa-Juan, Yang Hai-Zhen, Zhang Yan, Yang Wanling, Ma Jian-Yang, Zhao Ming-Hui, Shen Nan, Zhang Hong
Abstract excerpt
OBJECTIVE: Several novel susceptibility genes for systemic lupus erythematosus (SLE) and IgA nephropathy have been identified in recent genome-wide association studies. Since both lupus nephritis and IgA nephropathy are autoimmune diseases of the kidney, they may share common disease mechanisms that overlap with genetic susceptibility. To test this hypothesis, we sought to identify genetic variants associated...
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