Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of mitochondrial DNA mutations in brain tumors: A mini-review.

Journal of cancer research and therapeutics - 1 Jan 2000

Mohamed Yusoff Abdul Aziz

Abstract excerpt

Brain tumor is molecularly a heterogeneous group of diseases, and genetic factors seem to play a crucial role in its genesis. Even though multiple alterations in the nuclear-encoded genes such as tumor suppressor and oncogenes are believed to play a key role in brain tumorigenesis, the involvement of the mitochondrial genome to this event remains controversial to date. Mitochondrial DNA (mtDNA) has been suspected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Brain Neoplasms
Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to DNA, Mitochondrial

Share to Mutation

Source

Identifiers

PMID: 26458578
DOI: 10.4103/0973-1482.161925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of mitochondrial DNA mutations in brain tumors: A mini-review.PMID 26458578Read ↗

Mitochondrial Dysfunction: Effects and Therapeutic Implications in Cerebral Gliomas.Semantic proximity Read ↗

Somatic mitochondrial DNA mutations in different grades of glioma.Semantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma and Current Therapeutic Targets.Semantic proximity Read ↗

Mitochondrial DNA mutations in cancer--from bench to bedside.Semantic proximity Read ↗

Somatic mitochondrial DNA mutations in human cancers.Semantic proximity Read ↗

The importance of mitochondria in the tumourigenic phenotype: gliomas as the paradigm (review).Semantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma (GBM).Semantic proximity Read ↗

The mitochondrial genome is a "genetic sanctuary" during the oncogenic process.Semantic proximity Read ↗

Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer.Semantic proximity Read ↗

Mitochondrial DNA is a major source of driver mutations in cancer.Semantic proximity Read ↗

Mitochondrial defects in cancer.Semantic proximity Read ↗

Functional Role of Mitochondrial DNA in Cancer Progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.