Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Role of Mitochondrial DNA in Cancer Progression.

International journal of molecular sciences - 31 Jan 2022

Lin Yang-Hsiang, Lim Siew-Na, Chen Cheng-Yi, Chi Hsiang-Cheng, Yeh Chau-Ting, Lin Wey-Ran

Abstract excerpt

Mitochondrial DNA (mtDNA) has been identified as a significant genetic biomarker in disease, cancer and evolution. Mitochondria function as modulators for regulating cellular metabolism. In the clinic, mtDNA variations (mutations/single nucleotide polymorphisms) and dysregulation of mitochondria-encoded genes are associated with survival outcomes among cancer patients. On the other hand, nuclear-encoded genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Mitochondrial
Share to DNA, Neoplasm
Share to Mitochondria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mitochondrial Proteins

Share to Mutation

Share to Neoplasm Proteins

Share to Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 35163579
DOI: 10.3390/ijms23031659
PMCID: PMC8915179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Role of Mitochondrial DNA in Cancer Progression.PMID 35163579Read ↗

Somatic mitochondrial DNA mutations in human cancers.Semantic proximity Read ↗

Role of Mitochondrial DNA (mtDNA) Variations in Cancer Development: A Systematic Review.Semantic proximity Read ↗

Mitochondria act as a key regulatory factor in cancer progression: Current concepts on mutations, mitochondrial dynamics, and therapeutic approach.Semantic proximity Read ↗

Mitochondrial DNA alterations in precision oncology: Emerging roles in diagnostics and therapeutics.Semantic proximity Read ↗

Mitochondrial defects in cancer.Semantic proximity Read ↗

Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer.Semantic proximity Read ↗

Mitochondrial DNA variation and cancer.Semantic proximity Read ↗

Mitochondrial DNA is a major source of driver mutations in cancer.Semantic proximity Read ↗

Somatic mutations of mitochondrial DNA in aging and cancer progression.Semantic proximity Read ↗

Mitochondrial genome alterations in cancer: From mutations and epigenetics to targeted therapiesack.Semantic proximity Read ↗

Deregulated Mitochondrial DNA in Diseases.Semantic proximity Read ↗

Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.