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Article

Mitochondrial Dysfunction: Effects and Therapeutic Implications in Cerebral Gliomas.

Medicina (Kaunas, Lithuania) - 18 Nov 2024

Caruso Gerardo, Laera Roberta, Ferrarotto Rosamaria, Garcia Moreira Cristofer Gonzalo, Kumar Rajiv, Ius Tamara, Lombardi Giuseppe, Caffo Maria

Abstract excerpt

Gliomas are the most common primary brain tumors, representing approximately 28% of all central nervous system tumors. These tumors are characterized by rapid progression and show a median survival of approximately 18 months. The therapeutic options consist of surgical resection followed by radiotherapy and chemotherapy. Despite the multidisciplinary approach and the biomolecular role of targeted therapies, the...

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Identifiers

PMID: 39597073
DOI: 10.3390/medicina60111888
PMCID: PMC11596904

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