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Article

Mitochondrial defects in cancer.

Molecular cancer - 9 Dec 2002

Carew Jennifer S, Huang Peng

Abstract excerpt

Mitochondria play important roles in cellular energy metabolism, free radical generation, and apoptosis. Defects in mitochondrial function have long been suspected to contribute to the development and progression of cancer. In this review article, we aim to provide a brief summary of our current understanding of mitochondrial genetics and biology, review the mtDNA alterations reported in various types of cancer,...

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Source

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Identifiers

PMID: 12513701
DOI: 10.1186/1476-4598-1-9
PMCID: PMC149412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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