Article
Somatic mitochondrial DNA mutations in different grades of glioma.
Personalized medicine - 1 Jan 2022
Soon Bee Hong, Abu Nadiah, Abdul Murad Nor Azian, Then Sue-Mian, Abu Bakar Azizi, Fadzil Farizal, Thanabalan Jegan, Mohd Haspani Mohd Saffari, Toh Charng Jeng, Kumar Ramesh, Jaafar Ainul Syahrilfazli, Mohd Azli Anis Nabillah, Mohd Azahar Mohd Syakir, Paramasvaran Sanmugarajah, Palaniandy Kamalanathan, Mohd Tamil Azmi, Jamal Rahman
Abstract excerpt
Aim: Mitochondrial DNA (mtDNA) alterations play an important role in the multistep processes of cancer development. Gliomas are among the most diagnosed brain cancer. The relationship between mtDNA alterations and different grades of gliomas are still elusive. This study aimed to elucidate the profile of somatic mtDNA mutations in different grades of gliomas and correlate it with clinical phenotype. Materials &...
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