Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei.

The Journal of biological chemistry - 9 Oct 2015

McDermott Suzanne M, Guo Xuemin, Carnes Jason, Stuart Kenneth

Abstract excerpt

Uridine insertion and deletion RNA editing generates functional mitochondrial mRNAs in Trypanosoma brucei. The mRNAs are differentially edited in bloodstream form (BF) and procyclic form (PF) life cycle stages, and this correlates with the differential utilization of glycolysis and oxidative phosphorylation between the stages. The mechanism that controls this differential editing is unknown. Editing is catalyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Blood
Share to Life Cycle Stages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protozoan Proteins

Share to Ribonuclease III

Share to RNA Editing

Share to Tetracycline

Share to Trypanosoma brucei brucei

Source

Open in PubMed Open full text

Identifiers

PMID: 26304125
DOI: 10.1074/jbc.M115.669432
PMCID: PMC4599000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei.PMID 26304125Read ↗

The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes.Semantic proximity Read ↗

RNA editing in Trypanosoma brucei requires three different editosomes.Semantic proximity Read ↗

KREPA6 functions in RNA editing catalytic complex structural organization and gRNA utilization in Trypanosoma brucei.Semantic proximity Read ↗

The zinc-fingers of KREPA3 are essential for the complete editing of mitochondrial mRNAs in Trypanosoma brucei.Semantic proximity Read ↗

Multiple domains of the integral KREPA3 protein are critical for the structure and precise functions of RNA editing catalytic complexes in Trypanosoma brucei.Semantic proximity Read ↗

TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei.Semantic proximity Read ↗

RNA editing: complexity and complicationsSemantic proximity Read ↗

Dynamic RNA holo‐editosomes with subcomplex variants: Insights into the control of trypanosome editingSemantic proximity Read ↗

The Architecture of Trypanosoma brucei editosomesSemantic proximity Read ↗

Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex.Semantic proximity Read ↗

Deep mutational scanning of the RNase III-like domain in Trypanosoma brucei RNA editing protein KREPB4.Semantic proximity Read ↗

Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.